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SULFO-LC-SPDP


SULFO-LC-SPDP
Sulfosuccinimidyl-6-[3-(2-pyridyldithio)propionamido]hexanoate
Product Number: CLH127
CAS# 169751-10-4
Molecular Weight: 527.57
Spacer Arm 15.7 Â
Water-soluble, heterobifunctional, cleavable cross-linker.
Features/Benefits:
- Sulfo-LC-SPDP releases a detectable byproduct after reacting with free sulfhydryl groups; by measuring the release of pyridine-2-thione at 343 nm, the reaction can be easily followed
- Reactive groups: pyridyldithio and Sulfo-NHS ester
- Reactive toward: sulfhydryl and amino groups
Reference: Carlsson, J., et al. (1978) Biochem. J. 173, 723-737.