Sulfo-NHS-LC-Biotin

Sulfo-NHS-LC-Biotin
Sulfosuccinimidyl-6-(biotinamido)hexanoate
Product Number: BR110
CAS# [127062-22-0]

Molecular Weight: 556.59
Spacer Arm 22.4 Â

Offers a longer spacer arm than Sulfo-NHS-Biotin.

Features/Benefits
– Water-soluble analog of NHS-LC-Biotin
– Reacts with primary amines at pH 7-9 in non-amine-containing buffers such as borate, carbonate or phoshate buffers
– Negative charge of -SO 3 group keeps Biotinylation localized at the cell surface so reagent does not pass through cell membrane
– Sulfo-NHS ester group will start to hydolyze once it is dissolved in an aqueous buffer

REFERENCES: Hnatowich, D.J., KVirzi, F. and Ruschkowski, M. (1987) J. of Nuc. Med. 86, 1294-1302