LC-SPDP

LC-SPDP
Succinimidyl 6-[3-2-pyridyldithio)propionamido]hexanoate
Product Number: CLH125
CAS# 158913-22-5

Molecular Weight: 425.52
Melting Point: 92°C
Spacer Arm: 15.7Â

Classic heterobifunctional, cleavable cross-linker, with an extended arm.

Features/Benefits:
– LC-SPDP releases a detectable byproduct after reacting with a free sulfhydryl group; by measuring the release of pyridine-2-thione at 343 nm, the reaction can be easily followed
– Reactive groups: pyridyldithio and NHS ester
– Reactive toward: sulfhydryl and amino groups

Reference: Carlsson, J., et al. (1978) Biochem. J. 173, 723-737