Sulfo-NHS-Biotin

Sulfo-NHS-Biotin
N-Hydroxysulfosuccinimidyl biotin
Product Number: BR106
CAS# [119616-38-5]

Molecular Weight: 443.43
Spacer Arm 13.5 Â

Water soluble analog of NHS-Biotin.

Features/Benefits:
– Shorter spacer arm than Sulfo-NHS-LC-Biotin
– Reacts with primary amines at pH 7-9 in non-amine-containing buffers such as borate, carbonate or phosphate buffers
– Negative charge of -SO 3 keeps Biotinylation localized at the cell surface so reagent does not pass through cell membrane
– Eliminates the need for harmful organic solvents

REFERENCE: LEE, W.T. and CONRAD, D.H. (1984) J.Exp. Med. 159, 1790-1795