Biotinylation Reagents

Sulfo-NHS-SS-Biotin
(Sulfosuccinimidyl2(biotinamido) ethyl1,3dithiopropionate)
Disulfide bond in spacer arm is
cleavable by using reducing agents.

M.W. 606.69
Spacer Arm 24.3 Â

Features/Benefits
- Water-soluble and cleavable analog of NHS-LC-Biotin
- Ideal for reversible Biotinylation; biotin separated from molecule when spacer arm is cleaved
- Extended spacer arm prevents steric hindrance

REFERENCE: SHIMKUS, M., LEVY, T. and HERMAN, T. (1985) PNAS 82, 2593-2597